
Function reference
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PM_batch()
- Execute a Batch of PM_fit objects
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PM_cov
- Contains covariate data
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PM_cycle
- Pmetrics Run Cycle Information
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PM_data
- Defines the PM_data object
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PM_final
- Final Cycle Population Values
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PM_fit
- Object to define and run a model and data in Pmetrics
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PM_load()
- Load Pmetrics NPAG or IT2B output
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PM_model
- Defines the PM_model class
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PM_op
- Observed vs. predicted data
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PM_pop
- Population predictions at short intervals
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PM_post
- Individual Bayesian posterior predictions at short intervals
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PM_pta
- Define object for PTA
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PM_result
- Results of a Pmetrics run
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`$`
- Object to contain results of simulation
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PM_simlist
- Object to contain list of results of simulation
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PM_tutorial()
- Introductory tutorial to Pmetrics
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PM_valid
- Pmetrics validation object
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PMtree()
- Create a new Pmetrics folder tree
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PMcheckMatrix()
- Deprecated functions.
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makeAUC()
- Calculation of AUCs
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makeCov()
- Extract covariate data
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makeCycle()
- Summarize Pmetrics Run Cycle Information
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makeErrorPoly()
- Assay error polynomial coefficients
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makeFinal()
- Summarize NPAG or IT2B Final Cycle Population Values
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makeNCA()
- Non-compartmental analysis
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makeOP()
- Generated observed vs. predicted data
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makePTA()
- Calculation of PTAs
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makePTAtarget()
- Make PTA target object
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makePop()
- Individual Bayesian population prior predictions at short intervals
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makePost()
- Individual Bayesian posterior predictions at short intervals
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makeValid()
- Create a Pmetrics validation object
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make_NCA()
- Non-compartmental analysis
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make_valid()
- Create a Pmetrics validation object
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plot(<MMopt>)
- Plot Pmetrics Multiple-Model Optimal Sampling Objects
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plot(<PM_data>)
- Plot PM_data Time-Output Data
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plot(<PM_final>)
- Plot Pmetrics Final Cycle Parameter Value Distributions
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plot(<PM_op>)
- Plot PM_op objects
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plot(<PM_pta>)
- Plot PM_pta Percent Target Attainment objects
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plot(<PM_sim>)
- Plot Pmetrics Simulation Objects
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plot(<PM_simlist>)
- Plot list of Pmetrics Simulation Objects
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plot(<PM_valid>)
- Plot PM_valid objects
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plot(<PMcov>)
- Plot Pmetrics Covariate objects
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plot(<PMcycle>)
- Plot NPAG Cycle Information
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plot(<PMdopt>)
- Plot Pmetrics D-optimal Times
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plot(<PMfinal>)
- Plot Pmetrics Final Cycle Parameter Value Distributions
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plot(<PMmatrix>)
- Plot PMmatrix Time-Output Data
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plot(<PMop>)
- Plot PMop objects
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plot(<PMpta>)
- Plot PMpta Percent Target Attainment objects
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plot(<PMsim>)
- Plot Pmetrics Simulation Objects
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plot(<PMvalid>)
- Plot Pmetrics Validation Objects
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plot(<tidy_cov>)
- Wrapper function for plot.PMcov
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plot(<tidy_op>)
- Wrapper function for plot.PM_op
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ab_line()
- Add lines to plotly plot
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add_shapes()
- Add shapes to plotly plot
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summary(<PM_cov>)
- Wrapper function for summmary.PMcov
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summary(<PM_data>)
- Summarize a Pmetrics PM_data object
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summary(<PM_final>)
- Wrapper function for summmary.PMfinal
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summary(<PM_op>)
- Wrapper function for summmary.PMop
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summary(<PM_pta>)
- Wrapper function for summmary.PMpta
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summary(<PMcov>)
- Summarize Covariates and Bayesian Posterior Parameter Values
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summary(<PMdopt>)
- Summarize PMdopt objects
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summary(<PMfinal>)
- Summary Statistics for PMfinal Objects
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summary(<PMmatrix>)
- Summarize PMmatrix objects
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summary(<PMop>)
- Summarize Observations and Predictions
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summary(<PMpta>)
- Summarize Percent Target Attainment
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print(<MMopt>)
- Print Pmetrics Multiple-Model Optimal Sampling Objects
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print(<PMdopt>)
- Print PMdopt
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print(<PMerr>)
- Print Data Errors
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print(<PMnpc>)
- Print NPC
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print(<summary.PMfinal>)
- Print Summary of Parameter Values and Credibility Intervals
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print(<summary.PMmatrix>)
- Summarize Covariates and Bayesian Posterior Parameter Values
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print(<summary.PMop>)
- Print Summary of Observations and Predictions
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ERRrun()
- Execute an Assay Error Estimation run.
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ITrun()
- Execute an IT2B run.
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NPrun()
- Execute an NPAG run.
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SIMrun()
- Run the Pmetrics Simulator
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ITparse()
- Parse Pmetrics IT2B Output
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NPparse()
- Parse Pmetrics NPAG Output
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SIMparse()
- Parse Pmetrics Simulator Output
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PMload()
- Load Pmetrics NPAG or IT2B output (Legacy)
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qgrowth()
- Extract CDC pediatric growth charts
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zBMI()
- Extract CDC pediatric BMI z-scores
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ss.PK()
- Sample size calculations for Phase 1 PK study design
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mtsknn.eq()
- Multivariate two-sample test based on k-nearest neighbors
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PMcompare()
- Compare NPAG or IT2B runs
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PMgetCRCL()
- Add Jelliffe Creatinine Clearance
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PMstep()
- Stepwise covariate-parameter regressions
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ITex
- Example IT2B Output
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NPex
- Example NPAG Output
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badData
- Pmetrics data file with errors
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cdc_bmi
- CDC Pediatric and Adolescent BMI Table
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dataEx
- Pmetrics data file
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ger_bmi
- CDC Pediatric and Adolescent BMI Table
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growth
- CDC Pediatric and Adolescent Growth Data Table
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mic1
- Example MIC data
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modEx
- Pmetrics model object
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simEx
- Example simulator output
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NM2PM()
- Convert NONMEM to Pmetrics Data Files
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PMwrk2csv()
- Convert Old .wrk Files to .csv Matrix File
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PMmb2csv()
- Convert Old .mb or USC*PACK Files to .csv Matrix File
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PMmatrixRelTime()
- Convert Absolute Dates and Times to Relative Hours
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PMreadMatrix()
- Read a Pmetrics .csv Matrix Input File
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PMwriteMatrix()
- Write a Pmetrics .csv Matrix File
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PMFortranConfig()
- Read or define the Fortran compiler and command line template
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PMbuild()
- Build Pmetrics
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PMcheck()
- Check Pmetrics Inputs for Errors
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PMcode()
- Pmetrics GUI Tutor
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PMlogin()
- Login a user in the remote server
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PMlogout()
- Login a user in the remote server
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PMpatch()
- Download and install Pmetrics patches
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PMregister()
- Register a new user in the remote server
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PMreport()
- Summarize NPAG or IT2B Run
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ERRreport()
- Summarize ERR Run
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PMsave()
- Save Pmetrics objects
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PMtest()
- Test Pmetrics
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PMupdate()
- Download and install Pmetrics updates
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getPMoptions()
- Get Pmetrics User Options
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setPMoptions()
- Set Pmetrics User Options
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update_gfortran()
- Download and install Gfortran updates
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PMFortranConfig()
- Read or define the Fortran compiler and command line template
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PMmanual()
- Open user and function manuals.
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PMnews()
- Pmetrics changelog
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Pmetrics-package
Pmetrics
- Parametric and non-parametric modeling and simulation of pharmacokinetic-pharmacodynamic systems.