Function three_compartments_with_absorption

pub fn three_compartments_with_absorption(
    x: &Matrix<f64, Dyn, Const<1>, VecStorage<f64, Dyn, Const<1>>>,
    p: &Matrix<f64, Dyn, Const<1>, VecStorage<f64, Dyn, Const<1>>>,
    t: f64,
    rateiv: Matrix<f64, Dyn, Const<1>, VecStorage<f64, Dyn, Const<1>>>,
    _cov: &Covariates,
) -> Matrix<f64, Dyn, Const<1>, VecStorage<f64, Dyn, Const<1>>>
Expand description

Analytical solution for three compartment model with first-order absorption. Assumptions:

  • p is a vector of length 6 with ka, k10, k12, k13, k21 and k31 in that order. ka represents the absorption rate constant k10 represents the elimination rate constant from compartment 1 (central). The remaining parameters of the form kij represent the transfer rate constants from the ith to the jth compartment
  • rateiv is a vector of length 1 with the value of the infusion rate (only one drug)
  • x is a vector of length 4
  • covariates are not used